TOLUENE-4-SULFONIC ACID (S)-5-OXO-PYRROLIDIN-2-YLMETHYL ESTER
(S)-(+)-5-(hydroxymethyl)-2-pyrrolidinone P-tolu
CAS: 51693-17-5
Molecular Formula: C12H15NO4S
TOLUENE-4-SULFONIC ACID (S)-5-OXO-PYRROLIDIN-2-YLMETHYL ESTER - Names and Identifiers
| Name | (S)-(+)-5-(hydroxymethyl)-2-pyrrolidinone P-tolu |
| Synonyms | (-)-L-PYROGLUTAMOL P-TOLUENESULFONATE (S)-(+)-5-(hydroxymethyl)-2-pyrrolidinone P-tolu (S)-5-HYDROXYMETHYL-2-PYRROLIDINONE P-TOLUENESULFONATE [(2S)-5-oxopyrrolidin-2-yl]methyl 4-methylbenzenesulfonate (S)-(+)-5-(Hydroxymethyl)-2-pyrrolidinonep-toluenesulfonate (S)-(+)-5-(HYDROXYMETHYL)-2-PYRROLIDINONE P-TOLUENESULFONATE TOLUENE-4-SULFONIC ACID (S)-5-OXO-PYRROLIDIN-2-YLMETHYL ESTER 4-methylbenzenesulfonic acid [(2S)-5-oxo-2-pyrrolidinyl]methyl ester |
| CAS | 51693-17-5 |
| InChI | InChI=1/C12H15NO4S/c1-9-2-5-11(6-3-9)18(15,16)17-8-10-4-7-12(14)13-10/h2-3,5-6,10H,4,7-8H2,1H3,(H,13,14)/t10-/m0/s1 |
TOLUENE-4-SULFONIC ACID (S)-5-OXO-PYRROLIDIN-2-YLMETHYL ESTER - Physico-chemical Properties
| Molecular Formula | C12H15NO4S |
| Molar Mass | 269.32 |
| Density | 1.275±0.06 g/cm3(Predicted) |
| Melting Point | 124-128 °C (lit.) |
| Boling Point | 504.8±23.0 °C(Predicted) |
| Specific Rotation(α) | 8.5 º (c=1 in ethanol) |
| Flash Point | 259.1°C |
| Vapor Presure | 2.58E-10mmHg at 25°C |
| Appearance | Powder |
| Color | Colorless to beige |
| pKa | 15.34±0.40(Predicted) |
| Storage Condition | Sealed in dry,2-8°C |
| Refractive Index | 1.545 |
TOLUENE-4-SULFONIC ACID (S)-5-OXO-PYRROLIDIN-2-YLMETHYL ESTER - Risk and Safety
| Hazard Symbols | Xi - Irritant |
| Risk Codes | 36/37/38 - Irritating to eyes, respiratory system and skin. |
| Safety Description | S26 - In case of contact with eyes, rinse immediately with plenty of water and seek medical advice. S36 - Wear suitable protective clothing. |
| WGK Germany | 3 |
| HS Code | 29339980 |
TOLUENE-4-SULFONIC ACID (S)-5-OXO-PYRROLIDIN-2-YLMETHYL ESTER - Introduction
(S)-( )-5-(hydroxymethyl)-2-pyrrolidinone P-tolu is an organic compound with the chemical formula C11H15NO3S. The following is a description of its nature, use, preparation and safety information:
Nature:
(S)-( )-5-(hydroxymethyl)-2-pyrrolidinone P-tolu is a colorless to slightly yellow liquid with a special odor. It can be hydrolyzed under acidic conditions to (S)-(+)-5-hydroxymethyl-2-pyrrolidone and p-toluenesulfonic acid.
Use:
(S)-( )-5-(hydroxymethyl)-2-yrrolidinone P-tolu is commonly used as a reagent and intermediate in organic synthesis. It can be used in the synthesis of many drugs, optically active compounds and other organic compounds.
Preparation Method:
The preparation of (S)-( )-5-(hydroxymethyl)-2-pyrrolidinone P-tolu is usually carried out by esterification of p-toluenesulfonic acid and 2-pyrrolidone in an appropriate solvent. The addition of a certain acid catalyst in the reaction can improve the speed and yield of the reaction.
Safety Information:
(S)-( )-5-(hydroxymethyl)-2-pyrrolidinone P-tolu has low toxicity under general operating conditions. However, as a chemical, it still carries a certain degree of danger. During use, direct contact with skin and eyes should be avoided, and protective glasses and gloves should be worn if necessary. At the same time, it should be used in a well-ventilated place and avoid inhaling its vapor. During storage and handling, the relevant safety procedures shall be observed.
Nature:
(S)-( )-5-(hydroxymethyl)-2-pyrrolidinone P-tolu is a colorless to slightly yellow liquid with a special odor. It can be hydrolyzed under acidic conditions to (S)-(+)-5-hydroxymethyl-2-pyrrolidone and p-toluenesulfonic acid.
Use:
(S)-( )-5-(hydroxymethyl)-2-yrrolidinone P-tolu is commonly used as a reagent and intermediate in organic synthesis. It can be used in the synthesis of many drugs, optically active compounds and other organic compounds.
Preparation Method:
The preparation of (S)-( )-5-(hydroxymethyl)-2-pyrrolidinone P-tolu is usually carried out by esterification of p-toluenesulfonic acid and 2-pyrrolidone in an appropriate solvent. The addition of a certain acid catalyst in the reaction can improve the speed and yield of the reaction.
Safety Information:
(S)-( )-5-(hydroxymethyl)-2-pyrrolidinone P-tolu has low toxicity under general operating conditions. However, as a chemical, it still carries a certain degree of danger. During use, direct contact with skin and eyes should be avoided, and protective glasses and gloves should be worn if necessary. At the same time, it should be used in a well-ventilated place and avoid inhaling its vapor. During storage and handling, the relevant safety procedures shall be observed.
Last Update：2024-04-09 21:11:58
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Product Name: (S)-(+)-5-(Hydroxymethyl)-2-Pyrrolidinone p-Toluenesulfonate Visit Supplier Webpage Request for quotation
CAS: 51693-17-5
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Mobile: 18021002903
QQ: 3008007409
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CAS: 51693-17-5
Tel: 18301782025
Email: 3008007409@qq.com
Mobile: 18021002903
QQ: 3008007409
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